Colorectal malignancy

Abstract

Abstract Management of colorectal malignancy is a key area for most clinicians caring for patients with colorectal disease. This chapter forms a significant part of the overall text and gives in depth information about all aspects of colorectal malignancy. The chapter has been carefully updated from the first edition to include new evidence on molecular genetics, screening, polyp surveillance, and staging. New additions to the treatment sections include complete mesocolic excision, lateral lymph node dissection, and minimally invasive techniques such as TaTME, local excision, and robotic surgery. A comprehensive update of oncology pathways including neoadjuvant approaches such as ‘Watch and Wait’ is described. Management of locally advanced and metastatic disease is also covered, ranging from radical surgical interventions to supportive or palliative measures. Finally, the chapter covers tumour types other than colorectal adenocarcinoma, including anal SCC, NETs, lymphoma, GISTs, soft tissue sarcomas, and rare anal and pelvic tumours.