Psychotic Disorders: Comprehensive Conceptualization and Treatments emphasizes a dimensional approach to psychosis that cuts across a broad array of psychiatric diagnoses from schizophrenia to affective psychosis and organic disorders like epilepsy and dementias. Written by an international roster of over seventy leading experts in the field, this volume comprehensively reviews, critiques, and integrates available knowledge on the etiology, mechanisms, and treatments of psychotic disorders, and outlines ways forward in both research and clinical practice towards more objective, mechanistically-based definitions of psychotic disorders. Chapters address topics such as psychosis phenomenology, biomarkers and treatments, the overlaps and interfaces between psychiatric disorders within the psychosis dimension, and novel disease definitions. The book also incorporates findings on potential mechanisms, bridges between various system levels and their interactions, as well as the potential role in causation and/or mediation in psychotic disorders. Covering a broad array of treatment approaches and concluding with a section of forward perspectives, Psychotic Disorders aspires to stimulate new knowledge, generate novel frameworks, and carry new directions forward on psychotic disorders.