Atherosclerosis continues to be the most significant pathology giving rise to cardiovascular disease worldwide. Vascular biology forms the basic armamentarium to address the underlying mechanisms. The ESC Textbook of Vascular Biology discusses these new developments and recent breakthroughs in the field, while also covering the major changes in the diagnosis, prevention, and treatment of atherosclerosis that have occurred in recent years. This book offers a compendium of topics written by the best scientists in Europe. The dissemination of the authors’ vast knowledge and expertise in a single volume makes The ESC Textbook of Vascular Biology a useful companion for undergraduates in medicine and biology, but also for young scientists and early career staff. It also provides a comprehensive reference work for cardiologists and other clinical specialties dealing with vascular diseases and vascular imaging. The importance of vascular biology is crucial for the understanding of both physiological and pathophysiological processes in the vascular wall, and for accomplishing future endeavours in medical research.