Author:
Gandhi Rajesh T.,Juelg Boris,Jilg Nikolaus,Jakharia Niyati,Talwani Rohit
Abstract
Abstract
This chapter covers the HIV reservoir and cure and remission strategies. It details the importance of why we should try to cure HIV and includes clinical observations where the concept of a “functional cure” has been introduced. Early establishment and persistence of the latent HIV-1 reservoir are discussed as well as latency reversal approaches and latency silencing. A variety of immune-enhancing and/or immune-modulating strategies and immunomodulatory treatments are reviewed. Special attention is paid to therapeutic and preventive vaccines.
Publisher
Oxford University PressNew York