HIV and Hepatitis Coinfection

Abstract

Abstract This chapter discusses the epidemiology, clinical presentation, diagnosis, treatment, and complications of hepatitis B and hepatitis C in people with HIV. The learner will gain an understanding that all people with HIV should have a complete evaluation for hepatitis B. The chapter covers how to determine which patients are candidates for hepatitis B vaccinations and what treatments are appropriate for hepatitis B among patients living with HIV. The learner will also understand that patients with HIV who develop acute hepatitis C should be treated immediately and rescreened for potential reinfection. The chapter also discusses which direct-acting agents work best for patients with HIV and how antiretroviral therapy can be modified to reduce drug–drug interactions, disease severity, and cost considerations.