The importance of palliative care for children facing life-threatening illness and their families is now widely acknowledged as an essential part of care, which should be available to all children and families, throughout the child’s illness and at the end of life. The new edition of the Oxford Textbook of Palliative Care for Children brings together the most up to date information, current knowledge, evidence, and developments of clinical practice in the field. The main principles underlying this edition remain child and family-centred care, flexible and individualized care, evidence based and reflective practice, and teamwork. Structured into four sections. ‘Foundations of care’ describes core issues, the foundations on which paediatric palliative care is based. ‘Child and family care’ looks at different aspects of psychological, social, and cultural care for the sick child or young person, and their family. These chapters cover the time course of the illness, around the time of death and support for the bereaved family. ‘Symptom care’ focuses on the uses of medication, specific symptoms, and their management. Finally, ‘Delivery of care’ examines practical approaches to care in different environments and the needs of clinicians.