There is an evolution taking place regarding the nature and scope of the clinical goals of psychotherapeutic or counseling interventions in the palliative care setting. Meaning-Centered Psychotherapy in the Cancer Setting provides a theoretical context for meaning-centered psychotherapy (MCP), a nonpharmacologic intervention that has been shown to enhance meaning and spiritual well-being, increase hope, improve quality of life, and significantly decrease depression, anxiety, desire for hastened death, and symptom burden distress in the cancer setting. Based on the work of Viktor Frankl and his concept of logotherapy, MCP is an innovative intervention for clinicians practicing in fields of psycho-oncology, palliative care, bereavement, and cancer survivorship. This resource contains chapters on adapting MCP for different cancer-related populations and for different purposes and clinical problems, including interventions for cancer survivors, caregivers of cancer patients, adolescents and young adults with cancer, as a bereavement intervention, and cultural and linguistic applications in languages such as Mandarin, Spanish, and Hebrew.