Immune Reconstitution Inflammatory Syndrome (IRIS)-Reference-Cited by-同舟云学术

Immune Reconstitution Inflammatory Syndrome (IRIS)

Published:2023-10 Issue: Volume: Page:513-C42P66
ISSN:
Container-title:Fundamentals of HIV Medicine 2023
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Author:

Coppock Dagan

Abstract

Abstract This chapter aids the learner in understating the epidemiology of immune reconstitution inflammatory syndrome (IRIS) and associated opportunistic infections. IRIS is the inflammatory response of a rapidly restored immunologic function after starting antiretroviral therapy for HIV that can cause clinical deterioration. Opportunistic and other infections, previously unrecognized or tolerated by a failing immune system, may suddenly become targets of an overzealous restored immune system that can cause patients to become clinically worse, despite an otherwise excellent response to antiretroviral therapy. The learner will also recognize timing considerations regarding opportunistic infection treatment and antiretroviral therapy initiation related to IRIS, as well as management approaches to IRIS based on presenting and underlying opportunistic infections.

Publisher

Oxford University PressNew York

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