A Single Dose of Benzathine Penicillin G Is as Effective as Multiple Doses of Benzathine Penicillin G for the Treatment of HIV-Infected Persons With Early Syphilis-Reference-Cited by-同舟云学术

A Single Dose of Benzathine Penicillin G Is as Effective as Multiple Doses of Benzathine Penicillin G for the Treatment of HIV-Infected Persons With Early Syphilis

Published:2014-11-10 Issue:4 Volume:60 Page:653-660
ISSN:1058-4838
Container-title:Clinical Infectious Diseases
language:en
Short-container-title:

Author:

Ganesan Anuradha¹²,Mesner Octavio¹,Okulicz Jason F.¹³,O'Bryan Thomas¹³,Deiss Robert G.¹⁴,Lalani Tahaniyat¹⁵,Whitman Timothy J.¹²,Weintrob Amy C.¹²,Macalino Grace¹,Agan Brian K.¹

Affiliation:

1. Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland

2. Walter Reed National Military Medical Center, Washington, District of Columbia

3. San Antonio Military Medical Center, Texas

4. Naval Medical Center San Diego, California

5. Naval Medical Center Portsmouth, Virginia

Abstract

We examined treatment responses in >400 cases of early syphilis in human immunodeficiency virus-infected individuals. Serologic outcomes did not vary as a function of the treatment regimen. These results support the use of a single dose of benzathine penicillin as treatment.

Funder

Infectious Disease Clinical Research Program

National Institute of Allergy and Infectious Diseases

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Link

http://academic.oup.com/cid/article-pdf/60/4/653/28890361/ciu888.pdf

Reference25 articles.

1. Sexually transmitted diseases treatment guidelines, 2010;Workowski;MMWR Recomm Rep,2010

2. Dilemmas in the management of syphilis: a survey of infectious diseases experts;Dowell;Clin Infect Dis,2009

3. Invasion of the central nervous system by Treponema pallidum: implications for diagnosis and treatment;Lukehart;Ann Intern Med,1988

4. Prevalence of neurosyphilis in human immunodeficiency virus-infected patients with latent syphilis;Holtom;Am J Med,1992

5. Penicillin concentrations in cerebrospinal fluid (CSF) during repository treatment regimen for syphilis;van der Valk;Genitourin Med,1988

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