Detection of pentazocine and tripelennamine in urine.

Author:

Reid R W,Gerbeck C M

Abstract

Abstract Pentazocine and tripelennamine can be identified in urine as a part of routine screening for drug abuse. Pentazocine, pentazocine hydrate, and tripelennamine can be detected by thin-layer chromatography of chloroform/isopropanol extracts of heat- and acid-hydrolyzed urine. Gas chromatography is used for confirmation. Gas chromatographic/mass spectrometric studies (chemical ionization mode) show that such extracts contain major molecular (M+) ions of m/e 256, 286, and 304, indicating the presence of tripelennamine, pentazocine, and pentazocine hydrate, respectively.

Publisher

Oxford University Press (OUP)

Subject

Biochemistry, medical,Clinical Biochemistry

Cited by 9 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Applications of column-switching techniques in biopharmaceutical analysis;Journal of Chromatography B: Biomedical Sciences and Applications;1987-01

2. Luminol-dependent chemiluminescence of human neonatal polymorphonuclear leukocyte (PMN) activity;European Journal of Pediatrics;1986-04

3. Tripelennamine Hydrochloride;Analytical Profiles of Drug Substances;1985

4. Pentazocine;Analytical Profiles of Drug Substances;1984

5. Liquid Chromatographic Analysis of Pentazocine and Tripelennamine in Combination;Journal of Liquid Chromatography;1983-09

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