Nucleic Acid Concentrations in Normal Human Plasma

Author:

Kamm Richard C1,Smith Albert G1

Affiliation:

1. Department of Pathology, University of Tennessee Medical Units, Memphis, Tenn. 38103

Abstract

Abstract Utilizing a simple, rapid, and inexpensive modification of a fluorometric method, we determined the normal concentrations of nucleic acids (DNA and RNA) in human blood plasma of healthy individuals. DNA concentrations (13.9 ± 3.7 mg/ liter) were in excellent agreement with those reported by other methods. However, the RNA concentrations (144 ± 22 mg/liter) we found were higher than previously reported values, possibly because ribonuclease activity is more inhibited in this fluorometric method.

Publisher

Oxford University Press (OUP)

Subject

Biochemistry (medical),Clinical Biochemistry

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