Performance evaluation of multi-channel analyzers by use of linearly-related survey specimens.

Author:

Caragher T E,Grannis G F

Abstract

Abstract Sets of specimens having quantitative linear inter-relationships for 25 analytes were prepared and used in a small survey of results with multi-channel analyzers. Instrument calibration was evaluated by linear regression analysis of the analytical results, with calculation of the x- and y-intercepts and slopes. The average intercepts and slopes agreed quite well with those expected on the basis of specimen preparation, but the results from individual laboratories and from particular kinds of instruments demonstrated a variety of analytical biases. We conclude that performance of multi-channel analyzers can be evaluated effectively by such use of linearly related specimens in an inter-laboratory survey.

Publisher

Oxford University Press (OUP)

Subject

Biochemistry, medical,Clinical Biochemistry

Cited by 4 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

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3. IFCC Section;Clinical Chemistry and Laboratory Medicine;1982

4. Precision and Accuracy: Concepts and Assessment by Method Evaluation Testing;CRC Critical Reviews in Clinical Laboratory Sciences;1981-01

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