Age-related reference values for free amino acids in first morning urine specimens.

Author:

Parvy P R1,Bardet J I1,Rabier D M1,Kamoun P P1

Affiliation:

1. Laboratoire de Biochimie Médicale B, Hôpital Necker-Enfants Malades, Paris, France

Abstract

Abstract We determined age-related reference values for urinary free amino acids (in mmol/mol creatinine) in first morning urine specimens from 360 control subjects who were divided into nine age groups: birth to 1 month, 1-6 months, 6-12 months, 1-2 years, 2-4 years, 4-7 years, 7-10 years, 10-13 years, and older than 13 years. Except for taurine and 3-methylhistidine, the concentration of all the amino acids decreased with increasing age. The use of these results to detect aminoacidopathies and tubulopathies is discussed.

Publisher

Oxford University Press (OUP)

Subject

Biochemistry, medical,Clinical Biochemistry

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