Increased AutoAnalyzer Dialysis of Calcium and Magnesium in Presence of Protein

Author:

Lott John A1,Herman Thomas S1

Affiliation:

1. Department of Pathology, Ohio State University, 410 West 10th Ave., Columbus, Ohio 43210

Abstract

Abstract We have studied calcium and magnesium determination with the AutoAnalyzer, using dialysis, and measurement by atomic absorption spectrophotometry. The fraction of calcium and magnesium that dialyzes is proportional to the protein content of the sample; therefore an error is introduced when aqueous solutions of calcium or magnesium salts are used as standards. Apparently, the presence of proteins causes increased dialysis of Ca+2 and Mg+2.

Publisher

Oxford University Press (OUP)

Subject

Biochemistry (medical),Clinical Biochemistry

Cited by 9 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Determination of Calcium in Blood;Review Journal of Chemistry;2019-01

2. Magnesium content of serum, circulating mononuclear cells, skeletal muscle, and myocardium in congestive heart failure.;Circulation;1989-09

3. Analytical Reviews in Clinical Biochemistry: Calcium Measurement;Annals of Clinical Biochemistry: International Journal of Laboratory Medicine;1986-03

4. Calcium Measurements in Serum and Plasma—Total and Ionized;CRC Critical Reviews in Clinical Laboratory Sciences;1979-01

5. Automated development of analytical chemical methods;Analytica Chimica Acta;1977-12

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