Affiliation:
1. Mount Sinai Hospital Medical Center and The Chicago Medical School University of Health Sciences, California Ave. at 15th St., Chicago, Ill. 60608
Abstract
Abstract
A gas-chromatographic method is described for the quantitative determination of 11 barbiturates and glutethimide in blood. The extracted barbiturates are methylated and injected into a 7% DC-200 column. Use of methohexital as the internal standard, as well as the addition of standards to a drug-free sample of blood, compensates for losses and for differences in the distribution coefficient of the individual barbiturates, and makes the procedure highly precise and accurate.
Publisher
Oxford University Press (OUP)
Subject
Biochemistry, medical,Clinical Biochemistry
Cited by
20 articles.
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