An Automated Procedure for Blood Phenylalanine

Author:

Hill John B1,Summer George K1,Pender Murray W1,Roszel Norris O1

Affiliation:

1. Departments of Pharmacology and Pediatrics, University of North Carolina, Chapel Hill, N. C

Abstract

Abstract The fluorometric analysis of phenylalanine described by McCaman and Robins has been adapted to automation. The procedure may be used on 20-µl. whole-blood samples which may be stored on filter paper for elution. The procedure is rapid, reproducible, and accurate, making it useful for screening large populations for phenylketonuria.

Publisher

Oxford University Press (OUP)

Subject

Biochemistry (medical),Clinical Biochemistry

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