Transport of Beta-Carotene in Serum of Individuals with Carotenemia

Author:

Mathews-Roth Micheline M1,Gulbrandsen Christian L1

Affiliation:

1. Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, Mass.; the Channing Laboratory, Boston City Hospital, 774 Albany St., Boston, Mass. 02118; and the Department of Medicine, University of Hawaii School of Medicine, Honolulu, Hawaii

Abstract

Abstract We studied distribution of carotene in the various serum lipid fractions of carotenemic and noncarotenemic individuals. We found that the amount of carotene in each lipoprotein fraction is increased in the serum from carotenemic individuals, but that the relative increase is significant only in the low-density lipoprotein and high-density lipoprotein fractions. There was no significant difference between the cholesterol concentrations of each fraction of the carotenemic individuals' and noncarotenemic individuals' sera, indicating that serum betalipoprotein is not increased in carotenemia.

Publisher

Oxford University Press (OUP)

Subject

Biochemistry, medical,Clinical Biochemistry

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