Inhibition of Leukocyte Acid Phosphatase by Heparin-Reference-Cited by-同舟云学术

Inhibition of Leukocyte Acid Phosphatase by Heparin

Published:1972-12-01 Issue:12 Volume:18 Page:1532-1534
ISSN:0009-9147
Container-title:Clinical Chemistry
language:en
Short-container-title:

Author:

DeChatelet Lawrence R¹,McCall Charles E¹,Cooper M Robert¹,Shirley Pamela S¹

Affiliation:

1. Departments of Biochemistry and Medicine, The Bowman Gray School of Medicine, Winston-Salem, N.C. 27103

Abstract

Abstract Low concentrations of heparin (<1 unit/ml) inhibit by 80% the activity of leukocyte acid phosphatase. Leukocyte β-glucuronidase is less sensitive to heparin, and alkaline phosphatase and lysozyme are unaffected. The possible inhibitory effects of heparin should be considered in all measurements of leukocyte enzymatic activities.

Publisher

Oxford University Press (OUP)

Subject

Biochemistry (medical),Clinical Biochemistry

Link

http://academic.oup.com/clinchem/article-pdf/18/12/1532/32824600/clinchem1532.pdf

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