Rapid Method for Screening for Galactosemia and Galactokinase Deficiency by Measuring Galactose in Whole Blood Spotted on Paper

Abstract

Abstract An inexpensive automated fluorometric technique for blood galactose determination has been modified to use dried blood spots available through phenylketonuria screening programs. The method is more efficient because of its high capacity (≃85,000 tests a year), low cost (≃$3,000 a year in reagents), and high specificity (enzymatic method).