Beta-hCG vs intact hCG assays in the detection of trophoblastic disease.

Author:

Rinker A D1,Tietz N W1

Affiliation:

1. Department of Pathology, University of Kentucky Medical Center, Lexington 40536

Abstract

Abstract We describe a case of choriocarcinoma in which increased concentrations of beta-choriogonadotropin subunits in serum indicated recurrence of metastasis long before the tumor could be confirmed by visualization techniques, while intact choriogonadotropin remained normal (less than 5 int. units/L). Therefore, detection or monitoring of choriocarcinoma requires the assay of free beta-hCG subunit or an assay that measures both the free beta-subunit and intact choriogonadotropin.

Publisher

Oxford University Press (OUP)

Subject

Biochemistry (medical),Clinical Biochemistry

Cited by 6 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. How comparable are total human chorionic gonadotropin (hCGt) tumour markers assays?;Clinical Chemistry and Laboratory Medicine (CCLM);2019-07-24

2. Specificity of Different hCG Assays;Human Chorionic Gonadotropin;2010

3. Are Laboratories Reporting Serum Quantitative hCG Results Correctly?;Clinical Chemistry;2008-04-01

4. Human Chorionic Gonadotropin;Mayo Clinic Proceedings;1994-04

5. Clinical Use Of Hcg and hCGβ Determinations;Scandinavian Journal of Clinical and Laboratory Investigation;1993-01

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