Iron, transferrin, and ferritin in cerebrospinal fluid of children

Author:

Gruener Nachman1,Gozlan Orly1,Goldstein Tamara1,Davis Judith2,Besner irit3,Iancu Theodore C3

Affiliation:

1. Department of Clinical Biochemistry, Carmel Hospital, Haifa, Israel

2. The National Laboratory of Physics, Hebrew University, Jerusalem,Israel

3. Department of Pediatrics and Pediatric Research Unit, Carmel Hospital, and Faculty of Medicine, Technion-Israel Institute of Technology,Haifa, Israel

Abstract

Abstract We measured iron, ferritin, and transferrin in cerebrospinal fluid (CSF) of pediatric patients. Because the concentrations of iron and iron-binding proteins in CSF in these samples were lower than those ordinarily measured in older subjects, we had to modify the lower limit of detection of the methods used. The concentrations of these three analytes in patients with viral meningitis were higher than those in healthy infants and children.

Publisher

Oxford University Press (OUP)

Subject

Biochemistry, medical,Clinical Biochemistry

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