Rapid Detection of Prothrombotic Mutations of Prothrombin (G20210A), FactorV (G1691A), and Methylenetetrahydrofolate Reductase (C677T) by Real-Time Fluorescence PCR with the LightCycler
Author:
Affiliation:
1. Department of Clinical Chemistry, Georg-August-University, Robert Koch Strasse 40, 37075 Goettingen, Germany
Publisher
Oxford University Press (OUP)
Subject
Biochemistry (medical),Clinical Biochemistry
Link
http://academic.oup.com/clinchem/article-pdf/45/5/694/32721866/clinchem0694.pdf
Reference8 articles.
1. Factor V Leiden and other coagulation factor mutations affecting thrombotic risk
2. Mutation in blood coagulation factor V associated with resistance to activated protein C
3. A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis
4. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase
5. Real-time fluorescence genotyping of factor V Leiden during rapid-cycle PCR
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