Apolipoprotein E genotyping by capillary electrophoretic analysis of restriction fragments-Reference-Cited by-同舟云学术

Apolipoprotein E genotyping by capillary electrophoretic analysis of restriction fragments

Published:1997-08-01 Issue:8 Volume:43 Page:1321-1324
ISSN:0009-9147
Container-title:Clinical Chemistry
language:en
Short-container-title:

Author:

De Bellis Gianluca¹,Salani Giuliana¹,Panigone Silvia¹,Betti Ferruccio¹,Invernizzi Luigia¹,Luzzana Massimo²

Affiliation:

1. Consiglio Nazionale delle Ricerche, Istituto di Tecnologie Biomediche Avanzate, Via Fratelli Cervi 93, 20090 Segrate, Italy

2. Università degli Studi di Milano, Dipartimento di Scienze e Tecnologie Biomediche, Via Fratelli Cervi 93, 20090 Segrate, Italy

Abstract

AbstractWe present the genotyping of apolipoprotein (apo) E by means of restriction fragment analysis of amplified genomic DNA by high-performance capillary electrophoresis and a replaceable non-gel-sieving matrix. This procedure streamlines the genotyping of apo E in large-scale population studies because of the automation and speed of capillary electrophoresis.

Publisher

Oxford University Press (OUP)

Subject

Biochemistry (medical),Clinical Biochemistry

Link

http://academic.oup.com/clinchem/article-pdf/43/8/1321/32718192/clinchem1321.pdf

Reference12 articles.

1. Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology

2. Studies of familial type III hyperlipoproteinemia using as a genetic marker the apoE phenotype E2/2

3. Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

4. Apolipoprotein E and Alzheimer disease.

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