Hemopyrrole and kryptopyrrole are absent from the urine of schizophrenics and normal persons.

Author:

Gendler P L,Duhan H A,Rapoport H

Abstract

Abstract We describe a method for detecting hemopyrrole and kryptopyrrole in urine, with a detection limit of 100 mug/liter (1 part in 10(7)). Urine is thoroughly extracted with methylene chloride and the extract is concentrated and examined by gas chromatography and gas chromatography-mass spectrometry. No hemopyrrole or kryptopyrrole could be detected in 52 samples, from 17 controls, 29 schizophrenics, and six persons with acute intermittent porphyria.

Publisher

Oxford University Press (OUP)

Subject

Biochemistry, medical,Clinical Biochemistry

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