Specific Conductivity of Urine and Sensitivity of Enzyme Immunoassay Methods of Analysis for Drugs of Abuse

Author:

Andersen Ole1,Eriksen Peter Bonne1

Affiliation:

1. Department of Clinical Chemistry, Centralsygehuset i Naestved, 4700 Naestved, Denmark.

Abstract

Abstract We studied the sensitivity of the EMIT® assays of amphet-amine, benzodiazepines (diazepam), methadone, opiates (morphine), and propoxyphene at different specific con-ductivities in urine. The specific conductivity was varied by adding NaCI. For a sensitivity of 0.5 mg of drug per liter, the urine must have a specific conductivity of less than about 35 mS/cm in all these assays except that for ben¬zodiazepine, for which it must be less than about 20 mS/cm.

Publisher

Oxford University Press (OUP)

Subject

Biochemistry, medical,Clinical Biochemistry

Cited by 5 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Immunoassays in Forensic Toxicology;Encyclopedia of Analytical Chemistry;2006-09-15

2. Development of a latex agglutination inhibition reaction test for amphetamines in urine;Journal of Immunological Methods;1993-01

3. Problems of Mass Urine Screening for Misused Drugs;Journal of Psychoactive Drugs;1984-10-01

4. Enzyme Immunoassays in Clinical Chemistry: Present Status and Trends;Clinical Chemistry and Laboratory Medicine;1980

5. Enzyme Immunoassay: A Review;Annals of Clinical Biochemistry: International Journal of Laboratory Medicine;1979-01

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