A New Indicator for the Chelometric Measurement of Calcium in Serum and Urine

Author:

Catledge Gloria1,Biggs Homer G1

Affiliation:

1. Section of Clinical Chemistry, Department of Pathology, University Hospital and Hillman Clinic, Birmingham, Ala. 35233

Abstract

Abstract Hydroxy Naphthol Blue as a metallochromic indicator in the chelometric measurement of calcium with EDTA provides a very distinct color change at the end-point in the titration of aqueous solutions, serum, and urine samples. Iron, magnesium, copper, phosphate, and bilirubin in concentrations normally encountered in serum and urine did not interfere with the reaction of the indicator. The results obtained with this indicator were not statistically different from those of serum samples analyzed by flame photometry or urine samples analyzed chelometrically with Cal-Red as the indicator.

Publisher

Oxford University Press (OUP)

Subject

Biochemistry, medical,Clinical Biochemistry

Cited by 12 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Determination of Calcium in Blood;Review Journal of Chemistry;2019-01

2. Analytical Reviews in Clinical Biochemistry: Calcium Measurement;Annals of Clinical Biochemistry: International Journal of Laboratory Medicine;1986-03

3. Radiologische, Histologische und Biochemische Untersuchungen;Klinische Osteologie · A;1980

4. Calcium Measurements in Serum and Plasma—Total and Ionized;CRC Critical Reviews in Clinical Laboratory Sciences;1979-01

5. The use of hydroxynaphthol blue in the ultramicro-determination of alkaline earth and lanthanide elements: an improved method;Analytica Chimica Acta;1978-01

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