Dialysis-network variability in home dialysis use not explained by patient characteristics: a national registry-based cohort study in France

Author:

Couchoud Cécile12ORCID,Béchade Clémence3ORCID,Kolko Anne4,Baudoin Agnès Caillette5,Bayer Florian6,Rabilloud Muriel27,Ecochard René27,Lobbedez Thierry8ORCID

Affiliation:

1. REIN registry, Agence de la biomédecine , Saint-Denis La Plaine, France

2. Université Lyon I, CNRS, UMR 5558, Laboratoire de Biométrie et Biologie Evolutive , Equipe Biostatistique Santé, Villeurbanne France

3. Nephrology department, Caen University Hospital , Caen , France

4. Association pour l'Utilisation du Rein Artificiel en région Parisienne (AURA) Paris , Paris , France

5. Calydial, Lucien Hussel Hospital , Vienne , France

6. Direction Prélèvement Greffe Organes-Tissus, Agence de la biomédecine , Saint-Denis La Plaine, France

7. Hospices Civils de Lyon, Service de Biostatistique , Lyon , France

8. Nephrology department, Caen University Hospital , Caen, France

Abstract

ABSTRACT Background Although associated with better quality of life and potential economic advantages, home dialysis use varies greatly internationally and appears to be underused in many countries. This study aimed to estimate the dialysis-network variability in home dialysis use and identify factors associated with (i) the uptake in home dialysis, (ii) the proportion of time spent on home dialysis and (iii) home dialysis survival (patient and technique). Methods All adults ≥18 years old who had dialysis treatment during 2017–2019 in mainland France were included. Mixed-effects regression models were built to explore factors including patient or residence characteristics and dialysis network associated with variation in home dialysis use. Results During 2017–2019, 7728/78 757 (9.8%) patients underwent dialysis at least once at home for a total of 120 594/1 508 000 (8%) months. The heterogeneity at the dialysis-network level and to a lesser extent the regional level regarding home dialysis uptake or total time spent was marginally explained by patient characteristics or residence and dialysis-network factors. Between-network heterogeneity was less for patient and technique survival. These results were similar when the analysis was restricted to home peritoneal dialysis or home hemodialysis. Conclusions Variability between networks in the use of home dialysis was not fully explained by non-modifiable patient and residence characteristics. Our results suggest that to increase home dialysis use in France, one should focus on home dialysis uptake rather than survival. Financial incentives and a quality improvement programme should be implemented at the dialysis-network level to increase home dialysis use.

Publisher

Oxford University Press (OUP)

Subject

Transplantation,Nephrology

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