Preparing European Nephrology for the next pandemic: lessons from the ERACODA collaboration

Author:

Vart Priya12ORCID,Duivenvoorden Raphaël3,Franssen Casper F M1,Hemmelder Marc H4,Jager Kitty J5,Hilbrands Luuk B3ORCID,Noordzij Marlies1,Abramowicz Daniel67,Basile Carlo8,Covic Adrian9,Crespo Marta10,Massy Ziad A1112,Ortiz Alberto13ORCID,Emilio Sanchez J14ORCID,Petridou Emily15,White Colin16,Gansevoort Ron T1ORCID

Affiliation:

1. Department of Internal Medicine, University Medical Center Groningen, University of Groningen , Groningen , The Netherlands

2. Department of Clinical Pharmacy & Pharmacology, University Medical Center Groningen, University of Groningen , Groningen , The Netherlands

3. Department of Nephrology, Radboud University Medical Center , Nijmegen , The Netherlands

4. Department of Internal Medicine, Maastricht University Medical Center , Maastricht , The Netherlands

5. ERA Registry, Amsterdam UMC location University of Amsterdam, Medical Informatics, Meibergdreef 9; Amsterdam Public Health Research Institute, Quality of Care , Amsterdam , The Netherlands

6. Department of Nephrology, Antwerp University Hospital , Edegem , Belgium

7. Laboratory of Experimental Medicine and Pediatrics, University of Antwerp , Antwerp , Belgium

8. Division of Nephrology, Miulli General Hospital , Acquaviva delle Fonti , Italy

9. Grigore T. Popa University of Medicine and Pharmacy, Dr C.I. Parhon Hospital , Iasi , Romania

10. Department of Nephrology, Hospital del Mar, Mar Institute for Medical Research, Red de Investigación Renal (RICORS2040) (RD16/0009/0013) , Barcelona , Spain

11. Department of Nephrology, Centre Hospitalier Universitaire (CHU) Ambroise Paré, Assistance Publique-Hôpitaux de Paris (AP-HP) , Boulogne-Billancourt , France

12. Centre for Research in Epidemiology and Population Health (CESP), Institut National de la Santé et de la Recherche Médicale (INSERM) UMRS 1018, Team 5, University Versailles-Saint Quentin, University of Paris Saclay , Villejuif , France

13. Instituto de Investigación Sanitaria (IIS)-Fundación Jiménez Díaz, Autonomous University of Madrid (UAM), Red de Investigación Renal (REDINREN) , Madrid , Spain

14. Department of Nephrology, University Hospital of Cabuenes , Asturias , Spain

15. Representative of the European Kidney Patients’ Federation , Nicosia , Cyprus

16. Representative of the European Kidney Patients’ Federation , Dublin , Ireland

Abstract

ABSTRACTOwing to the vulnerability of patients with chronic kidney disease to infectious diseases, the coronavirus disease 2019 (COVID-19) pandemic has been particularly devastating for the nephrology community. Unfortunately, the possibility of future COVID-19 waves or outbreaks of other infectious diseases with pandemic potential cannot be ruled out. The nephrology community made tremendous efforts to contain the consequences of the COVID-19 pandemic. Despite this, the COVID-19 pandemic has highlighted several shortcomings in our response to the pandemic and has taught us important lessons that can be utilized to improve our preparedness for any future health crises of a similar nature. In this article we draw lessons from the European Renal Association COVID-19 Database (ERACODA) project, a pan-European collaboration initiated in March 2020 to understand the prognosis of COVID-19 in patients on kidney function replacement therapy. We discuss the challenges faced in generating timely and robust evidence for informed management of patients with kidney disease and give recommendations for our preparedness for the next pandemic in Europe. Limited collaboration, the absence of common data architecture and the sub-optimal quality of available data posed challenges in our response to COVID-19. Aligning different research initiatives, strengthening electronic health records, and involving experts in study design and data analysis will be important in our response to the next pandemic. The European Renal Association may take a leading role in aligning research initiatives via its engagement with other scientific societies, national registries, administrators and researchers.

Funder

European Renal Association

Dutch Kidney Foundation

Sandoz

Baxter

Publisher

Oxford University Press (OUP)

Subject

Transplantation,Nephrology

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