1. Division of Experimental Medicine, McGill University , Montreal,QC H4A 3J1, Canada
2. Centre for Clinical Epidemiology, Jewish General Hospital , Montreal, QC H3T 1E2, Canada
3. Division of Cardiology, Jewish General Hospital, McGill University , Montreal, QC H3T 1E2, Canada
4. Department of Kinesiology & Physical Education, McGill University, Montreal, QC H2W 1S4, Canada. Institution of research trial: Jewish General Hospital , Montreal, QC H3T 1E2 , Canada