Tear film dynamics with blinking and contact lens motion

Author:

Anderson Daniel M1,Corsaro Maria2,Horton Jonathan1,Reid Tim1,Seshaiyer Padmanabhan1

Affiliation:

1. Department of Mathematical Sciences, George Mason University, Fairfax, VA 22030, USA

2. Department of Mathematics, University of Notre Dame, Notre Dame, IN 46556, USA

Abstract

Abstract We develop a lubrication theory-based mathematical model that describes the dynamics of a tear film during blinking and contact lens (CL) wear. The model extends previous work on pre-corneal tear film dynamics during blinking by coupling the partial differential equation for tear film thickness to a dynamic model for CL motion. We explore different models for eyelid motion and also account for possible voluntary and involuntary globe (eyeball) rotation that may accompany blinking. Boundary conditions for mass flux at the eyelids are also adapted to account for the presence and motion of the CL. Our predictions for CL motion compare reasonably with existing data. Away from the eyelids the pre-lens tear film (PrLTF) is shifted, relative to its pre-corneal counterpart, in the direction of CL motion. Near the eyelids, the inflow/outflow of fluid under the eyelids also influences the PrLTF profile. We also compare our PrLTF dynamics to existing in vivo tear film thickness measurements.

Funder

US National Science Foundation, Computational Science Training for Undergraduates in the Mathematical Sciences

EXTREEMS-QED Undergraduate Research Program

REU Program

American Physical Society

Publisher

Oxford University Press (OUP)

Subject

Applied Mathematics,Pharmacology,General Environmental Science,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Modeling and Simulation,General Medicine,General Neuroscience

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