Long-Term Benefit of Golimumab for Patients with Moderately to Severely Active Ulcerative Colitis: Results from the PURSUIT-Maintenance Extension

Author:

Reinisch Walter1,Gibson Peter R2,Sandborn William J3,Feagan Brian G4,Strauss Richard5,Johanns Jewel5,Padgett Lakshmi5,Adedokun Omoniyi J5,Colombel Jean-Frederic6,Collins Judith7,Rutgeerts Paul8,Tarabar Dino9,Marano Colleen5

Affiliation:

1. Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria

2. Monash University and Alfred Hospital, Melbourne, VIC, Australia

3. Division of Gastroenterology, University of California San Diego, La Jolla, CA, USA

4. Robarts Research Institute, University of Western Ontario, London, ON, Canada

5. Immunology, Janssen Research & Development, LLC., Spring House, PA, USA

6. Icahn School of Medicine at Mount Sinai, New York, NY, USA

7. Oregon Health & Science University and Portland VA Medical Center, Portland, OR, USA

8. Division of Gastroenterology and Hepatology, University of Leuven, Gasthuisberg, Leuven, Belgium

9. Department of Gastroenterology, Military Medical Academy, Belgrade, Serbia

Funder

Janssen Research and Development

Publisher

Oxford University Press (OUP)

Subject

Gastroenterology,General Medicine

Reference9 articles.

1. Subcutaneous golimumab induces clinical response and remission in patients with moderate-to-severe ulcerative colitis;Sandborn;Gastroenterology,2014

2. Randomised clinical trial: a placebo-controlled study of intravenous golimumab induction therapy for ulcerative colitis;Rutgeerts;Aliment Pharmacol Ther,2015

3. Subcutaneous golimumab maintains clinical response in patients with moderate-to-severe ulcerative colitis;Sandborn;Gastroenterology,2014

4. Maintenance of efficacy and continuing safety of golimumab for active ulcerative colitis: PURSUIT-SC maintenance study extension through 1 year;Gibson;Clin Transl Gastroenterol,2016

5. Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. A randomized study;Schroeder;N Engl J Med,1987

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