Evaluation of a novel patient-specific quality assurance phantom for robotic single-isocentre, multiple-target stereotactic radiosurgery, and stereotactic radiotherapy

Author:

Xu Qianyi12ORCID,Vinogradskiy Yevgeniy2,Grimm Jimm3,Nie Wei1,Dupre Pamela1,Chawla Ashish K1,Bajaj Gopal1,Yang Haihua4,LaCouture Tamara2,Fan Jiajin1

Affiliation:

1. Department of Advanced Radiation Oncology and Proton Therapy, Inova Schar Cancer Institute , Fairfax, VA 22031, United States

2. Department of Radiation Oncology, Thomas Jefferson University , Philadelphia, PA 19107, United States

3. Department of Radiation Oncology, Wellstar Health System , Marietta, GA 30060, United States

4. Department of Radiation Oncology, Taizhou Hospital , Zhejiang 317000, China

Abstract

Abstract Objectives To evaluate patient-specific quality assurance (PSQA) of 3 targets in a single delivery using a novel film-based phantom. Methods The phantom was designed to rotate freely as a sphere and could measure 3 targets with film in a single delivery. After identifying the coordinates of 3 targets in the skull, the rotation angles about the equator and meridian were computed for optimal phantom setup, ensuring the film plane intersected the 3 targets. The plans were delivered on the CyberKnife system using fiducial tracking. The irradiated films were scanned and processed. All films were analysed using 3 gamma criteria. Results Fifteen CyberKnife test plans with 3 different modalities were delivered on the phantom. Both automatic and marker-based registration methods were applied when registering the irradiated film and dose plane. Gamma analysis was performed using a 3%/1 mm, 2%/1 mm, and 1%/1 mm criteria with a 10% threshold. For the automatic registration method, the passing rates were 98.2% ± 1.9%, 94.2% ± 3.7%, and 80.9% ± 6.3%, respectively. For the marker-based registration approach, the passing rates were 96.4% ± 2.7%, 91.7% ± 4.3%, and 78.4% ± 6.2%, respectively. Conclusions A novel spherical phantom was evaluated for the CyberKnife system and achieved acceptable PSQA passing rates using TG218 recommendations. The phantom can measure true-composite dose and offers high-resolution results for PSQA, making it a valuable device for robotic radiosurgery. Advances in knowledge This is the first study on PSQA of 3 targets concurrently on the CyberKnife system.

Publisher

Oxford University Press (OUP)

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