1. Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, Japan
2. Smidt Heart Institute, Cedars-SinaiMedical Center, 127 South San Vicente Boulevard, A3411, Los Angeles, California 90048, USA