1. Department of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart , Largo Francesco Vito, 1-00168 Rome , Italy
2. Department of Cardiovascular Medicine, Fondazione Policlinico Universitario A. Gemelli IRCCS , Largo Agostino Gemelli , 1–00168 Rome, Italy
3. Department of Medicine, University Campus Bio-Medico , Rome , Italy
4. Fondazione Policlinico Universitario Campus Bio-Medico , Rome , Italy