Multi-modality imaging in aortic stenosis: an EACVI clinical consensus document

Author:

Dweck Marc R1ORCID,Loganath Krithika1,Bing Rong1ORCID,Treibel Thomas A23,McCann Gerry P45ORCID,Newby David E1,Leipsic Jonathon6,Fraccaro Chiara7,Paolisso Pasquale89ORCID,Cosyns Bernard10,Habib Gilbert11ORCID,Cavalcante João12,Donal Erwan13ORCID,Lancellotti Patrizio1415ORCID,Clavel Marie-Annick1617ORCID,Otto Catherine M18,Pibarot Phillipe16

Affiliation:

1. Centre for Cardiovascular Science, University of Edinburgh , Chancellors Building, Little France Crescent, Edinburgh, EH16 4SB , UK

2. Barts Heart Centre, Bart's Health NHS Trust , W Smithfield, EC1A 7BE, London , UK

3. University College London Institute of Cardiovascular Science , 62 Huntley St, WC1E 6DD, London , UK

4. Department of Cardiovascular Sciences, University of Leicester , University Rd, Leicester LE1 7RH , UK

5. The NIHR Leicester Biomedical Research Centre , Glenfield Hospital, Groby Road, Leicester, LE3 9QP , UK

6. Centre for Cardiovascular Innovation, St Paul’s and Vancouver General Hospital , 1081 Burrard St Room 166, Vancouver, British Columbia V6Z 1Y6 , Canada

7. Department of Cardiac, Thoracic and Vascular Science and Public Health , Via Giustiniani, 2 - 35128, Padua , Italy

8. Cardiovascular Center Aalst, OLV Clinic , Moorselbaan 164, 9300 Aalst , Belgium

9. Department of Advanced Biomedical Sciences, University of Naples , Federico II, 80125 Naples , Italy

10. Department of Cardiology, Universitair Ziekenhuis Brussel , Laarbeeklaan 101, 1090 Jette , Belgium

11. Cardiology Department, Hôpital La Timone , 264 Rue Saint-Pierre, 13005 Marseille , France

12. Allina Health Minneapolis Heart Institute , Abbott Northwestern Hospital, 800 E 28th St, Minneapolis, MN 55407 , USA

13. Cardiology and CIC, Université Rennes , 2 Rue Henri Le Guilloux, 35033 Rennes , France

14. GIGA Cardiovascular Sciences, Department of Cardiology, University of Liège Hospital, CHU Sart Tilman , Liège , Belgium

15. Gruppo Villa Maria Care and Research , Corso Giuseppe Garibaldi, 11, 48022 Lugo RA , Italy

16. Institut Universitaire de Cardiologie et de Pneumologie de Québec/Québec Heart and Lung Institute , 2725 Ch Ste-Foy, Québec, QC G1V 4G5 , Canada

17. Faculté de Médecine—Département de Médecine, Université Laval , Ferdinand Vandry Pavillon, 1050 Av. de la Médecine, Québec City, Quebec G1V 0A6 , Canada

18. Division of Cardiology, Department of Medicine, University of Washington School of Medicine , 4333 Brooklyn Ave NE Box 359458, Seattle, WA 98195-9458 , USA

Abstract

Abstract In this EACVI clinical scientific update, we will explore the current use of multi-modality imaging in the diagnosis, risk stratification, and follow-up of patients with aortic stenosis, with a particular focus on recent developments and future directions. Echocardiography is and will likely remain the key method of diagnosis and surveillance of aortic stenosis providing detailed assessments of valve haemodynamics and the cardiac remodelling response. Computed tomography (CT) is already widely used in the planning of transcutaneous aortic valve implantation. We anticipate its increased use as an anatomical adjudicator to clarify disease severity in patients with discordant echocardiographic measurements. CT calcium scoring is currently used for this purpose; however, contrast CT techniques are emerging that allow identification of both calcific and fibrotic valve thickening. Additionally, improved assessments of myocardial decompensation with echocardiography, cardiac magnetic resonance, and CT will become more commonplace in our routine assessment of aortic stenosis. Underpinning all of this will be widespread application of artificial intelligence. In combination, we believe this new era of multi-modality imaging in aortic stenosis will improve the diagnosis, follow-up, and timing of intervention in aortic stenosis as well as potentially accelerate the development of the novel pharmacological treatments required for this disease.

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine,Radiology, Nuclear Medicine and imaging,General Medicine

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