Human airway mucus alters susceptibility of Pseudomonas aeruginosa biofilms to tobramycin, but not colistin

Author:

Müller Laura1,Murgia Xabier23,Siebenbürger Lorenz4,Börger Carsten4,Schwarzkopf Konrad5,Sewald Katherina1,Häussler Susanne67,Braun Armin1,Lehr Claus-Michael248,Hittinger Marius4,Wronski Sabine1

Affiliation:

1. Fraunhofer Institute for Toxicology and Experimental Medicine (Fraunhofer ITEM), Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Centre for Lung Research (DZL), Member of the REBIRTH Cluster of Excellence, Nikolai-Fuchs-Straße 1, Hannover, Germany

2. Helmholtz Institute for Pharmaceutical Research (HIPS), Helmholtz Centre for Infection Research, Universitätscampus E8.1, Saarbrücken, Germany

3. Korea Institute of Science and Technology, KIST Europe, Campus E7.1, Saarbrücken, Germany

4. PharmBioTec GmbH, Science Park 1, Saarbrücken, Germany

5. Department of Anaesthesia and Intensive Care, Klinikum Saarbrücken, Winterberg 1, Saarbrücken, Germany

6. Helmholtz Institute for Infection Research, Inhoffenstraße 7, Braunschweig, Germany

7. TWINCORE, Centre for Experimental and Clinical Infection Research, Feodor-Lynen-Straße 7, Hannover, Germany

8. Department of Pharmacy, Saarland University, Campus, Saarbrücken, Germany

Funder

Fraunhofer Institute for Toxicology

Helmholtz Institute for Pharmaceutical Research and PharmBioTec GmbH

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology,Microbiology (medical)

Reference52 articles.

1. Mucin structure, aggregation, physiological functions and biomedical applications;Bansil;Curr Opin Colloid Interface Sci,2006

2. Mucus clearance as a primary innate defense mechanism for mammalian airways;Knowles;J Clin Invest,2002

3. Clinical issues of mucus accumulation in COPD;Ramos;Int J Chron Obstruct Pulmon Dis,2014

4. Ex vivo sputum analysis reveals impairment of protease-dependent mucus degradation by plasma proteins in acute asthma;Innes;Am J Respir Crit Care Med,2009

5. Cystic fibrosis sputum: a barrier to the transport of nanospheres;Sanders;Am J Respir Crit Care Med,2000

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3