MALDI-TOF for the rapid detection of carbapenemase-producing Enterobacteriaceae: comparison of the commercialized MBT STAR®-Carba IVD Kit with two in-house MALDI-TOF techniques and the RAPIDEC® CARBA NP

Author:

Dortet Laurent123ORCID,Tandé Didier4,de Briel Dominique5,Bernabeu Sandrine123,Lasserre Camille4,Gregorowicz Guillaume5,Jousset Agnès B123,Naas Thierry123

Affiliation:

1. Department of Bacteriology-Hygiene, Hôpital de Bicêtre, Assistance Publique - Hôpitaux de Paris, Le Kremlin-Bicêtre, France

2. Associated French National Reference Center for Antibiotic Resistance, Le Kremlin-Bicêtre, France

3. Research Unit EA 7361 ‘Structure, dynamics, function and expression of broad spectrum β-lactamases’, Faculty of Medicine, University Paris-Sud, Le Kremlin-Bicêtre, France

4. Department of Microbiology, CHU de Brest, Brest, France

5. Department of Microbiology, Hôpitaux Civils de Colmar, Colmar, France

Funder

Santé Publique France

University Paris-Sud

Laboratory of Excellence in Research on Medication and Innovative Therapeutics

LERMIT

French National Research Agency

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology,Microbiology (medical)

Reference41 articles.

1. Global spread of carbapenemase-producing Enterobacteriaceae;Nordmann;Emerg Infect Dis,2011

2. Carbapenem resistance in Enterobacteriaceae: here is the storm!;Nordmann;Trends Mol Med,2012

3. Genetic and biochemical characterization of FRI-1, a carbapenem-hydrolyzing Class A β-lactamase from Enterobacter cloacae;Dortet;Antimicrob Agents Chemother,2015

4. Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases;Munoz-Price;Lancet Infect Dis,2013

5. Structural and functional aspects of class A carbapenemases;Naas;Curr Drug Targets,2016

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