Affiliation:
1. Pharmacology and Experimental Therapeutics Unit, School of Pharmacy, Institute for Drug Research, Faculty of Medicine, The Hebrew University of Jerusalem , Israel
Abstract
AbstractEosinophils are innate immune cells typically associated with allergic and parasitic diseases. However, in recent years, eosinophils have also been ascribed a role in keeping homeostasis and in fighting several infectious diseases. Indeed, these cells circulate as mature cells in the blood and can be quickly recruited to the infected tissue. Moreover, eosinophils have all the necessary cellular equipment such as pattern recognition receptors (PRRs), pro-inflammatory cytokines, anti-bacterial proteins, and DNA traps to fight pathogens and promote an efficient immune response. This review summarizes some of the updated information on the role of eosinophils’ direct and indirect mediated interactions with pathogens.
Funder
Emalie Gutterman Memorial Endowed Fund (USA), Israel Science Foundation
Aimwell Charitable Trust (UK), German-Israeli Foundation for Scientific Research and Development
Rosetrees Charitable Trust
Publisher
Oxford University Press (OUP)
Subject
Immunology,Immunology and Allergy
Cited by
13 articles.
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