Phytosphingosine is a novel activator of GPR120-Reference-Cited by-同舟云学术

Phytosphingosine is a novel activator of GPR120

Published:2018-01-24 Issue:1 Volume:164 Page:27-32
ISSN:0021-924X
Container-title:The Journal of Biochemistry
language:en
Short-container-title:

Author:

Nagasawa Tomotaka¹,Nakamichi Hikaru¹,Hama Yoichiro¹,Higashiyama Shigeki²,Igarashi Yasuyuki³,Mitsutake Susumu¹

Affiliation:

1. Laboratory of Food Safety and Science, Department of Applied Biochemistry and Food Science, Faculty of Agriculture, Saga University, Saga 840-8502, Japan

2. Division of Cell Growth and Tumor Regulation, Proteo-Science Center, Ehime University, Toon 791-0295, Japan

3. Laboratory of Biomembrane and Biofunctional Chemistry, Frontier Research Center for Advanced Material and Life Science, Hokkaido University, Sapporo 001-0021, Japan

Funder

Grant in Aid for Scientific Research (C)

Ministry of Education, Culture, Sports, Science and Technology, Japan

Publisher

Oxford University Press (OUP)

Subject

Molecular Biology,Biochemistry,General Medicine

Link

http://academic.oup.com/jb/article-pdf/164/1/27/25063462/mvy017.pdf

Reference24 articles.

1. Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120;Hirasawa;Nat. Med.,2005

2. Pharmacology and therapeutic implications of current drugs for type 2 diabetes mellitus;Tahrani;Nat. Rev. Endocrinol.,2016

3. Free fatty acid receptors FFAR1 and GPR120 as novel therapeutic targets for metabolic disorders;Hara;J. Pharm. Sci.,2011

4. The pharmacology of TUG-891, a potent and selective agonist of the free fatty acid receptor 4 (FFA4/GPR120), demonstrates both potential opportunity and possible challenges to therapeutic agonism;Hudson;Mol. Pharmacol,2013

5. Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human;Ichimura;Nature,2012

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