The minimal important difference of Saint George’s Respiratory Questionnaire in subjects with chronic pulmonary aspergillosis

Author:

Sehgal Inderpaul Singh1ORCID,Dhooria Sahajal1,Muthu Valliappan1ORCID,Prasad Kuruswamy Thurai1,Aggarwal Ashutosh Nath1,Chakrabarti Arunaloke2ORCID,Rudramurthy Shivaprakash M13ORCID,Agarwal Ritesh1

Affiliation:

1. Department of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research (PGIMER) , Chandigarh , India

2. Doodhadhari Burfani Hospital and Research Institute , Haridwar , India

3. Department of Medical Microbiology, Postgraduate Institute of Medical Education and Research (PGIMER) , Chandigarh , India

Abstract

Abstract The estimates of the minimal important difference (MID) for the Saint George’s Respiratory Questionnaire (SGRQ) score in chronic pulmonary aspergillosis (CPA) remain unknown. We performed a retrospective analysis on treatment-naïve CPA subjects (n = 148) treated with 6-month oral itraconazole therapy and completed SGRQ at baseline and 6 months. The study’s objective was to estimate the MID for SGRQ. We used an anchor-based method to determine the MID and found the MID for SGRQ of 7.3.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,General Medicine

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