Regioselectivity in the sulfonium-mediated arylation reactions of 2-substituted phenols with benzothienyl sulfoxide

Abstract

Abstract The regioselectivity in the sulfonium-mediated arylation of phenols with aryl sulfoxide is significantly influenced by the substituents at the 2 position of phenols. While most substituents tend to promote the expected C–C bond formation at the 6 position, alkyl substituents induce the minor formation of rearranged biaryls, the 1,2,3-substituted isomers.