The cGMP-Degrading Enzyme Phosphodiesterase-5 (PDE5) in Cerebral Small Arteries of Older People

Author:

Vasita Ekta1,Yasmeen Saiqa2,Andoh Joycelyn1,Bridges Leslie R3,Kruuse Christina2,Pauls Mathilde M H1,Pereira Anthony C4,Hainsworth Atticus H1

Affiliation:

1. Molecular and Clinical Sciences Research Institute, St. Georges University of London, London, United Kingdom

2. Department of Neurology, Herlev Hospital, Herlev Ringvej 75, 2730 Herlev, Denmark

3. Department of Cellular Pathology, St. George’s University Hospitals NHS Foundation Trust, Blackshaw Road, SW17 0QT, London, United Kingdom

4. Department of Neurology, St. George’s University Hospitals NHS Foundation Trust, London, Blackshaw Road, SW17 0QT, United Kingdom

Funder

Alzheimer’s Society

Alzheimer's Drug Discovery Foundation

Alzheimer’s Research UK

Publisher

Oxford University Press (OUP)

Subject

Cellular and Molecular Neuroscience,Clinical Neurology,Neurology,General Medicine,Pathology and Forensic Medicine

Reference19 articles.

1. Neuropathological assessment of the lesions of significance in vascular dementia;Esiri;J Neurol Neurosurg Psychiatry,1997

2. Risk factors and global cognitive status related to brain arteriolosclerosis in elderly individuals;Ighodaro;J Cereb Blood Flow Metab,2017

3. Biochemistry and physiology of cyclic nucleotide phosphodiesterases: Essential components in cyclic nucleotide signaling;Conti;Annu Rev Biochem,2007

4. Patterns of cerebral blood flow reduction in patients with ischemic leukoaraiosis;O'Sullivan;Neurology,2002

5. Perfusion by Arterial Spin labeling following Single dose Tadalafil In Small vessel disease (PASTIS): Study protocol for a randomised controlled trial;Pauls;Trials,2017

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