Glial Activation and Central Synapse Loss, but Not Motoneuron Degeneration, Are Prevented by the Sigma-1 Receptor Agonist PRE-084 in the Smn2B/− Mouse Model of Spinal Muscular Atrophy-Reference-Cited by-同舟云学术

Glial Activation and Central Synapse Loss, but Not Motoneuron Degeneration, Are Prevented by the Sigma-1 Receptor Agonist PRE-084 in the Smn2B/− Mouse Model of Spinal Muscular Atrophy

Published:2018-05-14 Issue:7 Volume:77 Page:577-597
ISSN:0022-3069
Container-title:Journal of Neuropathology & Experimental Neurology
language:en
Short-container-title:

Author:

Cerveró Clàudia¹,Blasco Alba¹,Tarabal Olga¹,Casanovas Anna¹,Piedrafita Lídia¹,Navarro Xavier²,Esquerda Josep E¹,Calderó Jordi¹

Affiliation:

1. Unitat de Neurobiologia Cel·lular, Departament de Medicina Experimental, Facultat de Medicina, Universitat de Lleida and Institut de Recerca Biomèdica de Lleida (IRBLLEIDA), Lleida, Catalonia, Spain

2. Group of Neuroplasticity and Regeneration, Institute of Neurosciences and Department of Cell Biology, Physiology and Immunology, Universitat Autònoma de Barcelona and CIBERNED, Bellaterra, Catalonia, Spain

Funder

Ministerio de Economía y Competitividad

FEDER

Publisher

Oxford University Press (OUP)

Subject

Cellular and Molecular Neuroscience,Clinical Neurology,Neurology,General Medicine,Pathology and Forensic Medicine

Link

http://academic.oup.com/jnen/article-pdf/77/7/577/25056173/nly033.pdf

Reference139 articles.

1. Molecular mechanisms of spinal muscular atrophy;Sumner;J Child Neurol,2007

2. Newborn and carrier screening for spinal muscular atrophy;Prior;Am J Med Genet A,2010