Study protocol for J-SUPPORT 1604 (J-FORCE): a randomized, double blind, placebo-controlled Phase III study evaluating olanzapine (5 mg) plus standard triple antiemetic therapy for prevention of chemotherapy induced nausea and vomiting in patients receiving cisplatin-based highly emetogenic chemotherapy

Author:

Hashimoto Hironobu1,Abe Masakazu2,Yanai Takako1,Yamaguchi Takuhiro3,Zenda Sadamoto456,Uchitomi Yosuke56,Fukuda Haruhiko7,Mori Mikio7,Iwasa Satoru8,Yamamoto Noboru9,Ohe Yuichiro10

Affiliation:

1. Department of Pharmacy, National Cancer Center Hospital

2. Department of Gynecologic Oncology, Shizuoka Cancer Center

3. Department of Biostatistics, Tohoku University Graduate School of Medicine

4. Department of Radiation Oncology, National Cancer Center Hospital East

5. Innovation Center for Supportive, Palliative and Psychosocial Care, National Cancer Center Hospital

6. Japan Supportive, Palliative and Psychosocial Oncology Group: J-SUPPORT

7. Data Management Section, National Cancer Center Hospital

8. Department of Gastrointestinal Medical Oncology, National Cancer Center Hospital

9. Department of Experimental Therapeutics, National Cancer Center Hospital

10. Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Radiology, Nuclear Medicine and imaging,Oncology,General Medicine

Reference11 articles.

1. Proposal for Classifying the Acute Emetogenicity of Cancer Chemotherapy;Hesketh;J Clin Oncol,1997

2. Randomized, double-blind, phase III trial of palonosetron versus granisetron in the triplet regimen for preventing chemotherapy-induced nausea and vomiting after highly emetogenic chemotherapy:TRIPLE study;Suzuki;Ann Oncol,2016

3. Radioreceptor binding profile of the atypical antipsychotic olanzapine;Bymaster;Neuropsychopharmacology,1996

4. Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding;Schotte;Psychopharmacology (Berl),1996

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