A randomized phase II/III trial of conventional paclitaxel and carboplatin with or without bevacizumab vs dose-dense paclitaxel and carboplatin with or without bevacizumab, in stage IVB, recurrent or persistent cervical carcinoma: Japan Clinical Oncology Group Study (JCOG1311)

Author:

Ishikawa Mitsuya1,Nakamura Kenichi2,Shibata Taro2,Tanaka Kiyo2,Kitagawa Ryo3,Kobayashi Hiroaki4,Yaegashi Nobuo5,

Affiliation:

1. Department of Gynecology, National Cancer Center Hospital, Tokyo, JAPAN

2. JCOG Data Center/Operations Office, National Cancer Center Hospital, Tokyo, JAPAN

3. Division of Obstetrics and Gynecology, Tohoku Medical and Pharmaceutical University, Miyagi, JAPAN

4. Department of Obstetrics & Gynecology, Faculty of Medicine, Kagoshima University, Kagoshima, JAPAN

5. Department of Obstetrics and Gynecology, Tohoku University School of Medicine, Miyagi, JAPAN

Funder

National Cancer Center Research and Development Fund

Medical Research and Development

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Radiology Nuclear Medicine and imaging,Oncology,General Medicine

Reference12 articles.

1. Phase III study of cisplatin with or without paclitaxel in stage IVB, recurrent, or persistent squamous cell carcinoma of the cervix: a gynecologic oncology group study;Moore;J Clin Oncol,2004

2. Randomized phase III trial of cisplatin with or without topotecan in carcinoma of the uterine cervix: a Gynecologic Oncology Group Study;Long;J Clin Oncol,2005

3. Phase III trial of four cisplatin-containing doublet combinations in stage IVB, recurrent, or persistent cervical carcinoma: a Gynecologic Oncology Group study;Monk;J Clin Oncol,2009

4. Improved survival with bevacizumab in advanced cervical cancer;Tewari;N Engl J Med,2014

5. A multi-institutional phase II trial of paclitaxel and carboplatin in the treatment of advanced or recurrent cervical cancer;Kitagawa;Gynecol Oncol,2012

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