Disease spreading modeling and analysis: a survey

Author:

Hiram Guzzi Pietro1,Petrizzelli Francesco2,Mazza Tommaso2

Affiliation:

1. Department of Surgical and Medical Sciences, Magna Graecia University , Catanzaro, 88110 , Italy

2. Bioinformatics unit, Fondazione IRCCS Casa Sollievo della Sofferenza , San Giovanni Rotondo, 71013 , Italy

Abstract

Abstract Motivation The control of the diffusion of diseases is a critical subject of a broad research area, which involves both clinical and political aspects. It makes wide use of computational tools, such as ordinary differential equations, stochastic simulation frameworks and graph theory, and interaction data, from molecular to social granularity levels, to model the ways diseases arise and spread. The coronavirus disease 2019 (COVID-19) is a perfect testbench example to show how these models may help avoid severe lockdown by suggesting, for instance, the best strategies of vaccine prioritization. Results Here, we focus on and discuss some graph-based epidemiological models and show how their use may significantly improve the disease spreading control. We offer some examples related to the recent COVID-19 pandemic and discuss how to generalize them to other diseases.

Funder

Italian Ministry of Health

Publisher

Oxford University Press (OUP)

Subject

Molecular Biology,Information Systems

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