Multi-modality artificial intelligence in digital pathology

Author:

Qiao Yixuan12,Zhao Lianhe1ORCID,Luo Chunlong12,Luo Yufan12,Wu Yang1,Li Shengtong3,Bu Dechao1,Zhao Yi124

Affiliation:

1. Research Center for Ubiquitous Computing Systems, Institute of Computing Technology, Chinese Academy of Sciences , Beijing 100190, China

2. University of Chinese Academy of Sciences , Beijing 100049, China

3. Massachusetts Institute of Technology , Cambridge, MA 02139, USA

4. Shandong First Medical University & Shandong Academy of Medical Sciences , Shandong Ji’nan 250117, China

Abstract

Abstract In common medical procedures, the time-consuming and expensive nature of obtaining test results plagues doctors and patients. Digital pathology research allows using computational technologies to manage data, presenting an opportunity to improve the efficiency of diagnosis and treatment. Artificial intelligence (AI) has a great advantage in the data analytics phase. Extensive research has shown that AI algorithms can produce more up-to-date and standardized conclusions for whole slide images. In conjunction with the development of high-throughput sequencing technologies, algorithms can integrate and analyze data from multiple modalities to explore the correspondence between morphological features and gene expression. This review investigates using the most popular image data, hematoxylin–eosin stained tissue slide images, to find a strategic solution for the imbalance of healthcare resources. The article focuses on the role that the development of deep learning technology has in assisting doctors’ work and discusses the opportunities and challenges of AI.

Funder

National Key Research and Development Program of China

Strategic Priority Research Program of the Chinese Academy of Sciences

Zhejiang Provincial Natural Science Foundation of China

Innovation Fund of Institute of Computing and Technology

Zhejiang Provincial Research Center for Cancer Intelligent Diagnosis and Molecular Technology

Shandong First Medical University & Shandong Academy of Medical Sciences

Publisher

Oxford University Press (OUP)

Subject

Molecular Biology,Information Systems

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