The association between body mass index and fibromyalgia severity: data from a cross-sectional survey of 2339 patients-Reference-Cited by-同舟云学术

The association between body mass index and fibromyalgia severity: data from a cross-sectional survey of 2339 patients

Published:2021 Issue:1 Volume:5 Page:
ISSN:2514-1775
Container-title:Rheumatology Advances in Practice
language:en
Short-container-title:

Author:

Atzeni Fabiola¹^ORCID,Alciati Alessandra²^ORCID,Salaffi Fausto³,Di Carlo Marco³^ORCID,Bazzichi Laura⁴,Govoni Marcello⁵,Biasi Giovanni⁶,Di Franco Manuela⁷,Mozzani Flavio⁸,Gremese Elisa⁹,Dagna Lorenzo¹⁰,Batticciotto Alberto¹¹,Fischetti Fabio¹²^ORCID,Giacomelli Roberto¹³,Guiducci Serena¹⁴,Guggino Giuliana¹⁵^ORCID,Bentivegna Mario¹⁶,Gerli Roberto¹⁷^ORCID,Salvarani Carlo¹⁸,Bajocchi Gianluigi¹⁹,Ghini Marco²⁰,Iannone Florenzo²¹^ORCID,Giorgi Valeria²²,Farah Sonia³^ORCID,Bonazza Sara⁵,Barbagli Stefano⁶,Gioia Chiara⁷,Marino Noemi Giuliana⁸,Capacci Annunziata⁹,Cavalli Giulio¹⁰,Cappelli Antonella¹¹,Carubbi Francesco¹³,Nacci Francesca¹⁴,Riccucci Ilenia¹⁷,Cutolo Maurizio²³,Sinigaglia Luigi²⁴,Sarzi-Puttini Piercarlo²²^ORCID

Affiliation:

1. Rheumatology Unit, Department of Internal Medicine, University of Messina, Messina

2. Department of Clinical Neurosciences, Hermanas Hospitalarias, Villa San Benedetto Menni Hospital, Albese con Cassano, Humanitas Clinical and Research Center, Como, Milan, Rozzano

3. Rheumatology Clinic, Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Jesi, Ancona

4. Rheumatology Unit, AOU Pisana, Pisa

5. Rheumatology, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliera-Universitaria S. Anna di Ferrara

6. Rheumatology Unit, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena

7. Rheumatology Unit, Department of Internal Medicine, Anesthesiological and Cardiovascular Sciences, Policlinico Umberto I, Sapienza University of Rome

8. Internal Medicine and Rheumatology Unit, Azienda Ospedaliero-Universitaria di Parma, Parma

9. Rheumatology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome

10. Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR), IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan

11. Rheumatology Unit, Internal Medicine Department, ASST Settelaghi, Varese

12. Unit of Rheumatology, Department of Medical, Surgery and Health Sciences, ASUGI and Clinical University, University of Trieste

13. Clinical Unit of Rheumatology, School of Medicine, University of L'Aquila

14. Division of Rheumatology AOUC, Department of Experimental and Clinical Medicine, University of Florence, Florence

15. Department of Health Promotion Sciences, Maternal and Infant Care, Internal Medicine and Medical Specialties, University of Palermo, Palermo

16. Integrated Reference Center of Rheumatology, Scicli Hospital, Ragusa

17. Rheumatology Unit, Department of Medicine, University of Perugia, Perugia

18. University of Modena and Reggio Emilia, Azienda USL-IRCCS di Reggio Emilia

19. Rheumatology Unit, S. Maria Hospital—USL, IRCCS Institute, Reggio Emilia

20. Rheumatology Unit, Azienda USL di Modena

21. Rheumatology Unit, Department of Emergency Surgery and Organ Transplantations, University of Bari, Bari

22. Rheumatology Unit, Internal Medicine Department, ASST Fatebenefratelli-Sacco, Milan University School of Medicine, Milan

23. Research Laboratory and Division of Clinical Rheumatology, Department of Internal Medicine, University of Genoa, IRCCS San Martino, Genova

24. Division of Rheumatology, ASST Gaetano Pini-CTO, Milano, Italy

Abstract

Abstract Objective Various studies have shown that overweight and obesity are central features of FM, but the real impact of a high BMI on clinical severity in patients with FM is still controversial. The aim of this study was to analyse the relationships between BMI categories and measures of symptom severity and functional impairment using data from a Web-based registry of patients with FM. Methods Adult patients with an ACR 2010/2011 diagnosis of FM underwent a complete physical examination and laboratory tests and were asked to complete a package of questionnaires covering their sociodemographic and treatment details, in addition to the following disease-specific questionnaires: the revised Fibromyalgia Impact Questionnaire (FIQR), the modified Fibromyalgia Assessment Status questionnaire (ModFAS) and the Polysymptomatic Distress Scale (PDS). Results A total of 2339 patients were recruited and divided into two weight categories, underweight/normal (U/N, n = 1127, 48.2%) and overweight/obese (O/O, n = 1212, 51.8%). The total and subscales of FIQR, ModFAS and PSD scores were significantly higher in the O/O patients, as were all the mean scores of the individual FIQR items (P < 0.001 for all). Conclusion Our findings demonstrate that O/O patients with FM are significantly more impaired than U/N patients in all the symptomatological and functional domains as measured using the FIQR, ModFAS and PDS, thus suggesting that being O/O has an additional effect on symptoms and function.

Publisher

Oxford University Press (OUP)

Subject

Rheumatology

Link

http://academic.oup.com/rheumap/advance-article-pdf/doi/10.1093/rap/rkab015/36416644/rkab015.pdf

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