High Prevalence of Late-Stage Disease in Newly Diagnosed Human Immunodeficiency Virus Patients in Sierra Leone-Reference-Cited by-同舟云学术

High Prevalence of Late-Stage Disease in Newly Diagnosed Human Immunodeficiency Virus Patients in Sierra Leone

Published:2018-08-23 Issue:9 Volume:5 Page:
ISSN:2328-8957
Container-title:Open Forum Infectious Diseases
language:en
Short-container-title:

Author:

Yendewa George A¹²³^ORCID,Poveda Eva⁴,Lakoh Sulaiman⁵,Yendewa Sahr A⁵,Jiba Darlinda F⁵,Salgado-Barreira Angel⁶,Sahr Foday⁵⁷,Salata Robert A¹²

Affiliation:

1. Department of Medicine, Case Western Reserve University, Cleveland, Ohio

2. Division of Infectious Diseases and HIV Medicine, University Hospitals Cleveland Medical Center, Ohio

3. Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland

4. Group of Virology and Pathogenesis, Galicia Sur Health Research Institute (IIS Galicia Sur)-Complexo Hospitalario Universitario de Vigo, SERGAS-UVigo, Spain

5. College of Medicine and Allied Health Sciences, University of Sierra Leone, Freetown

6. Methodology and Statistics Unit, Galicia Sur Health Research Institute (IIS Galicia Sur)-Complexo Hospitalario Universitario de Vigo, SERGAS-UVigo, Spain

7. 34 Military Hospital, Republic of Sierra Leone Armed Forces, Freetown

Abstract

Abstract A high prevalence of late-stage disease (75.4%) and severe immunosuppression (23.3%) was observed in 155 newly diagnosed human immunodeficiency virus patients in Freetown, Sierra Leone during August to November 2017. Within the late-stage diagnosis group, a significantly high proportion of patients reported fever (84.2% vs 65.2%; P = .01), weight loss (82.2% vs 63.5%; P = .01), and malaise (89.7% vs 71.7%; P = .05). Fever was identified as the only independent predictor of late-stage disease in this study.

Funder

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Link

http://academic.oup.com/ofid/article-pdf/5/9/ofy208/33576024/ofy208.pdf

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