Canary in the Coal Mine? Transmitted Mutations Conferring Resistance to All Integrase Strand Transfer Inhibitors in a Treatment-Naive Patient-Reference-Cited by-同舟云学术

Canary in the Coal Mine? Transmitted Mutations Conferring Resistance to All Integrase Strand Transfer Inhibitors in a Treatment-Naive Patient

Published:2018-11-01 Issue:11 Volume:5 Page:
ISSN:2328-8957
Container-title:Open Forum Infectious Diseases
language:en
Short-container-title:

Author:

McGee Kara S¹,Okeke Nwora Lance¹,Hurt Christopher B²,McKellar Mehri S¹

Affiliation:

1. Department of Medicine, Division of Infectious Diseases, Duke University Medical Center, Durham, North Carolina

2. Institute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill

Abstract

Abstract Transmitted drug resistance to the integrase strand transfer inhibitor (INSTI) class of antiretrovirals is very rare. We present a case of a treatment-naive female patient with human immunodeficiency virus harboring resistance to all INSTIs, including bictegravir and dolutegravir.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Link

http://academic.oup.com/ofid/article-pdf/5/11/ofy294/33629676/ofy294.pdf

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